A Nurse Practitioner (NP) is a registered nurse (RN) with advanced training in diagnosing and treating illness. Nurse Practitioners prescribe medications, treat illness, and administer physical exams. NPs differ from physicians in that they focus on prevention, wellness, and education. NPs specialize in providing all encompassing individualized care. Most NPs specialize in particular areas of health care. Many NPs work in primary & acute care settings.